Recently the term extremophile has been used to describe these organisms over the past twenty years extensive studies of the ecology physiology taxonomy and molecular biology of these micro organisms have been undertaken these have resulted in a complete reassessment of our concept ofmicrobial evolution. Bioprospecting and biotechnology of extremophiles submission closed comment overview articles authors from the thermophilic bacteria eg thermus aquaticus from hydrothermal environments without doubt the advances in molecular biology and life science during last decades would not have been possible without these extremozymes . Note citations are based on reference standards however formatting rules can vary widely between applications and fields of interest or study the specific requirements or preferences of your reviewing publisher classroom teacher institution or organization should be applied. Over the last decades the study of extremophiles has provided ground breaking discoveries that challenge our understanding of biochemistry and molecular biology in the applied side extremophiles and their enzymes have spawned a multibillion dollar biotechnology industry with applications spanning biomedical pharmaceutical industrial . References 8 molecular biology and biotechnology of microbial interactions with organic and inorganic heavy metal compounds 81 introduction 82 physiology of metal microbe interactions 83 molecular biology of heavy metal tolerance 831 plasmid mediated bacterial heavy metal resistance 832 metal binding proteins of fungi 84
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