Male infertility is a complex multifactorial pathological condition in which genetic factors have roles men with azoospermia are at the highest risk of being carriers of genetic anomalies 25 . Men who may have had unexplained infertility in the past may now be diagnosed with genetic causes of infertility through recently available testing in fact this field is progressing so quickly that genetic infertility has already become one of the most commonly diagnosed reasons for male infertility. Infertility is a major health problem today affecting about 150 of couples trying to have a child impaired fertility of the male is causative in 200 of infertile couples and contributory in up to another 300 400 infertility already affects about 50 70 of the general male population . Some genetic problems such as y chromosome deletions will be passed on to any male child born through the use of sperm in ivf or icsi procedures however for most men with presumed genetic causes of infertility we dont yet know whether their children will be affected. Genetics of male infertility our male infertility specialist yefim r sheynkin make an appointment it is clear that a significant proportion of infertile male with azoospermia and severe oligospermia have a genetic etiology for reproductive failure
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